Myc‐driven tumorigenesis involves a non‐transcriptional role for Myc in over‐activating replicative Cdc45‐MCM‐GINS (CMG) helicases. Excessive stimulation of CMG helicases by Myc mismanages CMG function by diminishing the number of reserve CMGs necessary for fidelity of DNA replication and recovery from replicative stresses. One potential outcome of these events is the creation of DNA damage that alters genomic structure/function, thereby acting as a driver for tumorigenesis and tumor heterogeneity. Intriguingly, another potential outcome of this Myc‐induced CMG helicase over‐activation is the creation (...) of a vulnerability in cancer whereby tumor cells specifically lack enough unused reserve CMG helicases to recover from fork‐stalling drugs commonly used in chemotherapy. This review provides molecular and clinical support for this provocative hypothesis that excessive activation of CMG helicases by Myc may not only drive tumorigenesis, but also confer an exploitable “reserve CMG helicase vulnerability” that supports developing innovative CMG‐focused therapeutic approaches for cancer management. (shrink)

Hume's Reception in Early America: Expanded Edition brings together the original American responses to one of Britain's greatest men of letters, David Hume. Now available as a single volume paperback, this new edition includes updated further readings suggestions and dozens of additional primary sources gathered together in a completely new concluding section. From complete pamphlets and booklets, to poems, reviews, and letters, to extracts from newspapers, religious magazines and literary and political journals, this book's contents come from a wide variety (...) of sources published in colonial America and the early United States between 1758 and 1850. As well as classics by Thomas Jefferson, John Adams and Alexander Hamilton, it contains scores of unknown and hard-to-locate items, many of which have not been reprinted since their original publication. These responses are divided into four parts covering Hume's Essays; his Philosophical Writings; his History of England; and his Character and Death. Each of those parts has a separate introductory essay, and every selection is introduced by a short headnote that sets the piece in its historical context and provides bibliographical references. Packed with new insights into Hume and American thought and culture, Hume's Reception in Early America reveals the relevance and impact of Hume on American political, philosophical, historical, religious, and aesthetic debates. (shrink)

At the heart of this three-part volume are three dozen previously unpublished Adam Ferguson letters—written between 13 September 1784 and 13 April 1811—and a previously unpublished essay by him on...

More is known about the pervasiveness of college cheating than reasons why students cheat. This article reports the results of a study that applied the theory of reasoned action and partial least squares methodology to analyze the responses of 144 students to a survey on cheating behavior. Approximately 60% of the business students and 64% of the non-business students admitted to such behavior. Among cheaters, a "desire to get ahead" was the most important motivating factor - a surprising result given (...) the comprehensive set of factors tested in the study. Among non-cheaters, the presence of a "moral anchor" such as an ethical professor was most important. The article also includes a set of important caveats that might limit this study and suggests some avenues for further study. (shrink)

A thorough examination of the role which David Hume''s writings played upon the founders of the United States.This book explores the reception of David Hume''s political thought in eighteenth-century America. It presents a challenge to standard interpretations that assume Hume''s thought had little influence in early America. Eighteenth-century Americans are often supposed to have ignored Hume''s philosophical writings and to have rejected entirely Hume''s "Tory" History of England. James Madison, if he used Hume''s ideas in Federalist No. 10, it is (...) commonly argued, thought best to do so silently -- open allegiance to Hume was a liability. Despite renewed debate about the impact of Hume''s political ideas in America, existing scholarship is often narrow and highly speculative. Were Hume''s works available in eighteenth-century America? If so, which works? Where? When? Who read Hume? To what avail? To answer questions of that sort, this books draws upon a wide assortment of evidence. Early American book catalogues, periodical publications, and the writings of lesser-light thinkers are used to describe Hume''s impact on the social history of ideas, an essential context for understanding Hume''s influence on many of the classic texts of early American political thought. Hume''s Essays and Treatises on Several Subjects, was readily available, earlier, and more widely, than scholars have supposed. The History of England was read most frequentlyof all, however, and often in distinctive ways. Hume''s History, which presented the British constitution as a patch-work product of chance historical developments, informed the origins of the American Revolution and Hume''ssubsequent reception through the late eighteenth century. The 326 subscribers to the first American edition of Hume''s History (published in Philadelphia in 1795-96) are more representative of the History''s friendlyreception in enlightened America than are its few critics. Thomas Jefferson''s latter-day rejection of Hume''s political thought foreshadowed Hume''s falling reputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006). periodical publications, and the writings of lesser-light thinkers are used to describe Hume''s impact on the social history of ideas, an essential context for understanding Hume''s influence on many of the classic texts of early American political thought. Hume''s Essays and Treatises on Several Subjects, was readily available, earlier, and more widely, than scholars have supposed. The History of England was read most frequentlyof all, however, and often in distinctive ways. Hume''s History, which presented the British constitution as a patch-work product of chance historical developments, informed the origins of the American Revolution and Hume''ssubsequent reception through the late eighteenth century. The 326 subscribers to the first American edition of Hume''s History (published in Philadelphia in 1795-96) are more representative of the History''s friendlyreception in enlightened America than are its few critics. Thomas Jefferson''s latter-day rejection of Hume''s political thought foreshadowed Hume''s falling reputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006).eputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006). periodical publications, and the writings of lesser-light thinkers are used to describe Hume''s impact on the social history of ideas, an essential context for understanding Hume''s influence on many of the classic texts of early American political thought. Hume''s Essays and Treatises on Several Subjects, was readily available, earlier, and more widely, than scholars have supposed. The History of England was read most frequentlyof all, however, and often in distinctive ways. Hume''s History, which presented the British constitution as a patch-work product of chance historical developments, informed the origins of the American Revolution and Hume''ssubsequent reception through the late eighteenth century. The 326 subscribers to the first American edition of Hume''s History (published in Philadelphia in 1795-96) are more representative of the History''s friendlyreception in enlightened America than are its few critics. Thomas Jefferson''s latter-day rejection of Hume''s political thought foreshadowed Hume''s falling reputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006). periodical publications, and the writings of lesser-light thinkers are used to describe Hume''s impact on the social history of ideas, an essential context for understanding Hume''s influence on many of the classic texts of early American political thought. Hume''s Essays and Treatises on Several Subjects, was readily available, earlier, and more widely, than scholars have supposed. The History of England was read most frequentlyof all, however, and often in distinctive ways. Hume''s History, which presented the British constitution as a patch-work product of chance historical developments, informed the origins of the American Revolution and Hume''ssubsequent reception through the late eighteenth century. The 326 subscribers to the first American edition of Hume''s History (published in Philadelphia in 1795-96) are more representative of the History''s friendlyreception in enlightened America than are its few critics. Thomas Jefferson''s latter-day rejection of Hume''s political thought foreshadowed Hume''s falling reputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006).eputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006).eputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006). periodical publications, and the writings of lesser-light thinkers are used to describe Hume''s impact on the social history of ideas, an essential context for understanding Hume''s influence on many of the classic texts of early American political thought. Hume''s Essays and Treatises on Several Subjects, was readily available, earlier, and more widely, than scholars have supposed. The History of England was read most frequentlyof all, however, and often in distinctive ways. Hume''s History, which presented the British constitution as a patch-work product of chance historical developments, informed the origins of the American Revolution and Hume''ssubsequent reception through the late eighteenth century. The 326 subscribers to the first American edition of Hume''s History (published in Philadelphia in 1795-96) are more representative of the History''s friendlyreception in enlightened America than are its few critics. Thomas Jefferson''s latter-day rejection of Hume''s political thought foreshadowed Hume''s falling reputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006).eputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in the Atlantic World (2006).rough the late eighteenth century. The 326 subscribers to the first American edition of Hume''s History (published in Philadelphia in 1795-96) are more representative of the History''s friendlyreception in enlightened America than are its few critics. Thomas Jefferson''s latter-day rejection of Hume''s political thought foreshadowed Hume''s falling reputation in nineteenth-century America. MARK G. SPENCER is Associate Professor of History at Brock University where he holds a Chancellor''s Chair for Research Excellence. His books include Hume''s Reception in Early America (2002), Utilitarians and Their Critics in America, 1789-1914 (2005),and Ulster Presbyterians in. (shrink)

Hume's works in Colonial and early Revolutionary America -- Historiographical context for Hume's reception in eighteenth-century America -- Hume's earliest reception in Colonial America -- Hume's impact on the prelude to American independence -- Humean origins of the American Revolution -- Hume and Madison on faction -- Was Hume a liability in late eighteenth-century America? -- Explaining "Publius's" silent use of Hume -- The reception of Hume's politics in late eighteenth-century America.

This study takes as its point of departure a question posed by Francis Hutcheson in An Inquiry into the Original of Our Ideas of Beauty and Virtue, an important text of the Scottish Enlightenment. Hutcheson asked: “Whence arises this Love of Esteem, or Benevolence, to good Men, or to Mankind in general, if not from some nice Views of Self-Interest?” . As will be well known to readers of this journal, Hutcheson in his answer pointed to the workings of a (...) “moral sense,” arguing: “The Universality of this moral Sense, and that it is antecedent to Instruction, may appear from observing the Sentiments of Children, upon hearing the Storys with which they are commonly entertain’d as soon as they understand Language. They always passionately interest themselves on that side where Kindness and Humanity are found; and detest the Cruel, the Covetous, the Selfish, or the Treacherous. How strongly do we see their Passions of Joy, Sorrow, Love, and Indignation, mov’d by these moral Representations, even tho there has been no pains taken to give them Ideas of a Deity, of Laws, of a future State, or of the more intricate Tendency of the universal Good to that of each Individual!”. (shrink)

Both communitarianism and casuistry have sought to restore ethics as a practical science—the former by incorporating various traditions into a shared definition of the common good, the latter by considering the circumstances of each situation through critical reasoning. Mark G. Kuczewski analyzes the origins and methods of these two approaches and forges from them a new unified approach. This approach takes the communitarian notion of the person as its starting point but also relies upon the narrative and analogical tools (...) of case-based reasoning. He separates out the rhetoric that is incongruent with the Aristotelian aspirations of each method to show that the two are complementary, and that consensus can emerge from fragmentation. He then applies his resulting method to three major problems in bioethics: the difficulties that the issue of personal identity poses for advance directives, the role of the family in medical decision making, and the refusal of treatment because of religious beliefs. He analyzes the need to assume a communitarian notion of the person as a starting point for the application of casuistic insights. Combining theoretical, practical, and scholarly insights, this book will be of interest to philosophers, political and social scientists, and bioethicists. (shrink)

Contemporary bioethics has been somewhat skewed by its focus on high-tech medicine and the resulting development of ethical frameworks based on an acute-care model of healthcare. Research and scholarship in bioethics have payed only cursory attention to ethical issues related to disability. I argue that bioethics should concern itself with the full range of theoretical and practical issues related to disability. This encounter with the disability community will enrich bioethics and, potentially, society as well. I suggest a number of items (...) that the bioethics agenda should include, such as the development of a casuistry of the right to healthcare and to community integration and an advocacy role in fostering an understanding among the public and policy makers of the need to reform research and treatment related to disability. (shrink)

Ran is one of the most abundant and best conserved of the small GTP binding and hydrolyzing proteins of eukaryotes. It is located predominantly in cell nuclei. Ran is a member of the Ras family of GTPases, which includes the Ras and Ras‐like proteins that regulate cell growth and division, the Rho and Rac proteins that regulate cytoskeletal organization and the Rab proteins that regulate vesicular sorting. Ran differs most obviously from other members of the Ras family in both its (...) nuclear localization, and its lack of sites required for post‐translational lipid modification. Ran is, however, similar to other Ras family members in requiring a specific guanine nucleotide exchange factor (GEF) and a specific GTPase activating protein (GAP) as stimulators of overall GTPase activity. In this review, the multiple cellular functions of Ran are evaluated with respect to its known biochemistry and molecular interactions. (shrink)

I analyze the insights present in Elisabeth Kübler-Ross’s seminal work, On Death and Dying that have laid the foundation for contemporary clinical bioethics as it is practiced by clinical ethics co...

Epistemology -- Power I -- Power II -- Subjectivity -- Resistance -- Critique -- Ethics.

Introduction: Foucault and political philosophy -- Marx: antinormative critique -- Lenin: the invention of party governmentality -- Althusser: the failure to denormativise Marxism -- Deleuze: denormativisation as norm -- Rorty: relativising normativity -- Honneth: the poverty of critical theory -- Geuss: the paradox of realism -- Foucault: the lure of neoliberalism -- Conclusion: What now?

In lieu of an abstract, here is a brief excerpt of the content:Hume Studies Volume 29, Number 1, April 2003, pp. 89-98 Another "Curious Legend" about Hume's An Abstract of a Treatise of Human Nature MARK G. SPENCER I In 1938, J. M. Keynes and P. Sraffa edited and introduced for Cambridge University Press a reprinting of An Abstract of A Treatise of Human Nature.1 The Abstract they claimed in their subtitle was "A Pamphlet hitherto unknown by DAVID HUME." (...) Arguing against a number of nineteenth and early-twentieth -century scholars who attributed authorship of an abstract of the Treatise to Adam Smith, Keynes and Sraffa convincingly documented in their introductory essay many solid reasons for thinking that the pamphlet being reprinted was Hume's.2 Sixty years on, their account dispelling this "curious legend" of Smith's authorship has now become the received opinion. T.E. Jessop accepted Keynes and Sraffa's argument (having seen it in proof before the edition was published) in his bibliography of 1938, and Norman Kemp Smith gave their version an early supportive review.3 E.C. Mossner, in his well-known biography of Hume, accepted wholeheartedly Keynes and Sraffa's findings.4 When in 1978 the Selby-Bigge's edition of Hume's Treatise saw its second edition the text of the Abstract was appended and a note gave P.H. Nidditch's opinion that "Hume's authorship is overwhelmingly likely."5 More recently Mark G. Spencer is Social Sciences and Humanities Research Council of Canada Postdoctoral Research Fellow, Department of History, University of Toronto. Sidney Smith Hall, 100 St. George St., Toronto, Ontario MSS 3GS, Canada. [email protected] 90 Mark G. Spencer in the pages of this journal, Jeff Broome, David Raynor, and David Fate Norton have all helped buttress the case for Hume's authorship, as did R. W. Connon and M. Pollard elsewhere.6 Despite an occasional dissenting voice,7 the Abstract is now widely, and rightly (or so it seems to this author), thought to have been Hume's. But with all of this scholarly attention focused on confirming Hume's authorship, another much more contentious aspect of Keynes and Sraffa's interpretation has gone largely unnoticed. Keynes and Sraffa's billing of the Abstract as "A Pamphlet hitherto unknown by DAVID HUME," suggested that before 1938 the Abstract had not been attributed publicly to Hume and that the contents of the pamphlet also had been completely unknown. "Students of Hume have known that an abstract of the Treatise was made and intended for publication," wrote a reviewer of Keynes and Sraffa, "[b]ut no copy of this abstract was known to exist: indeed it was usually supposed that the abstract had never been printed at all."8 Relying on Keynes and Sraffa it would be easy to suppose that the Abstract was never publicly ascribed to Hume and even that the contents of the pamphlet had been overlooked entirely until Keynes and Sraffa came along. One of the purposes of the present short essay is to dispel, once and for all, that misunderstanding about the Abstract. Norman Kemp Smith went part of the way toward that end in 1938 when he reviewed Keynes and Sraffa's edition. But in the process Kemp Smith introduced another "curious legend" that has slipped into scholarly acceptance with little comment and no debate. We will see that it is a mistake to argue, as Kemp Smith did, that Hume's authorship of a sixpenny pamphlet was known to readers of An universal biographical and historical dictionary, published in 1800. There is no discussion of Hume's Abstract in that book. However, the Abstract was discussed in print in at least three different publications between 1818 and 1827, long after its initial publication in 1740 and long before Keynes and Sraffa brought it to the attention of their audience in 1938. While pre-1938 Hume scholars had overlooked the Abstract, at least one of Hume's early nineteenth-century critics knew of the Abstract's existence, attributed the work to Hume, and even quoted extensively from Hume's "Preface." Most interesting of all, Hume's authorship of the Abstract was interpreted in ways that are telling of the historical reception of... (shrink)

This book outlines and evaluates the principal strands of critical legal studies, and achieves much more as well.

Originally published in 1999, this classic textbook includes twenty-six cases with commentary and bibliographic resources designed especially for medical students and the training of ethics consultants. The majority of the cases reflect the day-to-day moral struggles within the walls of hospitals typically described as community hospitals; as a result, the cases do not focus on esoteric, high-tech dilemmas--viz., genetic engineering or experimental protocols--but rather on fundamental problems that are pervasive in basic healthcare delivery in the United States: where to send (...) a frail, elderly patient who refuses to go to a nursing home; what role the family should play in making a treatment decision; what a hospital should do when it is getting stuck with too many unpaid bills. This thoroughly revised and updated second edition includes thirteen new cases, five of which are designated as "skill builder" cases aimed specifically for those participants in the Neiswanger Institute for Bioethics' web-based instructional program. This edition has also been restructured for teachability, and will feature reformatted and revised commentaries. (shrink)

The evaluation of new theories and pedagogical approaches to business ethics is an essential task for ethicists. This is true not only for empirical and applied evaluation but also for metatheoretical evaluation. However, while there is increasing interest in the practical utility and empirical testing of ethical theories, there has been little systematic evaluation of how new theories relate to existing ones or what novel conceptual characteristics they might contribute. This paper aims to address this lack by discussing the role (...) of metatheorising in assessing new approaches to ethics. The approach is illustrated through evaluating a new pedagogy and curriculum for ethics education called Giving Voice to Values (GVV). Our method involves identifying a number of metatheoretical lenses from existing reviews of ethical theories and applying these to examine GVV’s conceptual elements. Although GVV has been explicitly presented as a pedagogy and teaching curriculum, we argue that it has the potential to contribute significantly to the development of ethical theory. We discuss the general implications of this metatheoretical method of evaluation for new approaches to business ethics and for GVV and its future development. (shrink)

Bioethicists think about families in terms of conflicting interests. This mistake results from an impoverished notion of informed consent. Only by adequately characterizing the process of informed consent can we capture the phenomenon of shared decisionmaking.

This is a clear and critical account of Foucault's political thought: what he said, how it's been used and its influence today. Michel Foucault, French philosopher, social theorist, historian of ideas and literary critic, is primarily known as a radical thinker who disturbs our understanding of society, yet little attention has been paid to his politics. Now, Mark Kelly details and criticises all of Foucault's major political ideas: the historical relativity of knowledge; exclusion and abnormality; his radical reconception of (...) power; his historical analysis of biopolitics in terms of discipline and biopower; his concept of governmentality; and his late work around ethics and subjectivity. Kelly shows how Foucault's positions changed over time, how his thought has been used in the political sphere and examines the importance of his work for politics today. It engages with Foucault's entire corpus, from his first works right up to his posthumously published College de France lectures and the unabridged version of the History of Madness. It looks at the theoretical reception of Foucault's thought and how it has been applied to real-world problems. (shrink)

Political philosophers since Hobbes often construe social life in terms of a conflict which is rarely reconciled, but rather is accommodated in politics or adjudicated in law. Yet many think that morality pertains even in a formalized situation of attenuated agreement. Following Rawls, this morality is held to be a minimal, incipient, rudimentary form of justice--in Rawls's case, fairness. I argue from Kierkegaard and Habermas that a minimal, incipient, rudimentary form of love--namely, hospitality, the welcome of strangers--is equiprimordial to fairness (...) in establishing the basic social situation. (shrink)

I consider the problem liberalism poses for bioethics.Liberalism is a view that advocates that the state remain neutralto views of the good life. This view is sometimes supported by askeptical moral epistemology that tends to propel liberalismtoward libertarianism. I argue that the possibilities for sharedagreement on moral matters are more promising than is sometimesappreciated by such a view of liberalism. Using two examples ofpublic debates of moral issues, I show that commonly sharedintuitions may ground moral principles even if they may (...) be givendifferent weight by persons of different moral and religioustraditions. Nevertheless, the fact that the intuition andprinciple is widely shared may be sufficient to chart somedirections for public policy or cooperative action even if theydo not lead to complete agreement. As a result, I argue that aliberal communitarianism that presupposes a fairly minimalistepistemology is a legitimate approach to achieving sharedagreement in a pluralistic society. (shrink)

A step-by-step guide to Foucault's History of Sexuality Volume I, The Will to KnowledgeIn the first volume of his History of Sexuality, The Will to Knowledge, Foucault weaves together the most influential theoretical account of sexuality since Freud. Mark Kelly systematically unpacks the intricacies of Foucault's dense and sometimes confusing exposition, in a straightforward way, putting it in its historical and theoretical context.This is both a guide for the reader new to the text and one that offers new insights (...) to those already familiar with Foucault's work. (shrink)

Communitarian critics have derided case-based reasoning for ignoring the need to arrive at a shared hierarchy of goods prior to case.

It has become common in medical ethics to discuss difficult cases in terms of the principles of respect for autonomy, beneficence, nonmaleficence, and justice. These moral concepts or principles serve as maxims that are suggestive of appropriate clinical behavior. Because this language evolved primarily in the acute care setting, I consider whether it is in need of supplementation in order to be useful in the long-term care setting. Through analysis of two typical cases involving residents of long-term care facilities, I (...) argue for the additional principles of candor and responsibility for narrative integrity. (shrink)

Spirituality or religion often presents as a foreign element to the clinical environment, and its language and reasoning can be a source of conflict there. As a result, the use of spirituality or religion by patients and families seems to be a solicitation that is destined to be unanswered and seems to open a distance between those who speak this language and those who do not. I argue that there are two promising approaches for engaging such language and helping patients (...) and their families to productively engage in the decision-making process. First, patient-centered interviewing techniques can be employed to explore the patient's religious or spiritual beliefs and successfully translate them into choices. Second, and more radically, I suggest that in some more recalcitrant conflicts regarding treatment plans, resolution may require that clinicians become more involved, personally engaging in discussion and disclosure of religious and spiritual worldviews. I believe that both these approaches are supported by rich models of informed consent such as the transparency model and identify considerations and circumstances that can justify such personal disclosures. I conclude by offering some considerations for curbing potential unprofessional excesses or abuses in discussing spirituality and religion with patients. (shrink)

The economic theory of the consumer, which assumes individual satisfaction as its goal and individual freedom to pursue satisfaction as its sine qua non, has become an important ideological element in political economy. Some have argued that the political dimension of economics has evolved into a kind of “secular theology” that legitimates free market capitalism, which has become a kind of “religion” in the United States [Nelson: 1991, Reaching for Heaven on Earth: The Theological Meaning of Economics. (Rowman & Littlefield (...) Publishers, Inc, Savage, Maryland); 2001, Economics as Religion: From Samuelson to Chicago and Beyond (The Pennsylvania State University Press, University Park, Pennsylvania); Thurow: 1983, Dangerous Currents: The State of Economics (Random House, New York); Milbank: 1990, Theology and Social Theory, Beyond Secular Reason (Basil Blackwell, Cambridge, Massachusetts)]. Consumer theory in its ideological form provides an important base for this religion and is no longer merely a positive framework for understanding consumer choice or estimating market demand. The paper explores the view of the human being, the “anthropology,” that is implicit in the economic theory of the consumer and compares its “theological” implications with the corresponding theological anthropologies in the Judaeo-Christian tradition. The paper outlines the assumptions of consumer theory and then focuses on three aspects of the theory from a critical theological perspective: the individual in community, property ownership, and human destiny (or “eschatology” in theological terminology). The principal conclusion is that consumer theory, viewed from this perspective, leads to a reductionist and existentially harmful view of human beings. The maximization of individual satisfaction raises genuine ethical issues when viewed as a political and religious value. The paper argues that the issues could be ameliorated if economists would include more explicit treatment of a social dimension and ethical alternatives in consumer theory and if theologians would give greater attention to economic theory. (shrink)

The economic theory of the consumer, which assumes individual satisfaction as its goal and individual freedom to pursue satisfaction as its sine qua non, has become an important ideological element in political economy. Some have argued that the political dimension of economics has evolved into a kind of "secular theology" that legitimates free market capitalism, which has become a kind of "religion" in the United States [Nelson: 1991, Reaching for Heaven on Earth: The Theological Meaning of Economics. ; 2001, Economics (...) as Religion: From Samuelson to Chicago and Beyond ; Thurow: 1983, Dangerous Currents: The State of Economics ; Milbank: 1990, Theology and Social Theory, Beyond Secular Reason ]. Consumer theory in its ideological form provides an important base for this religion and is no longer merely a positive framework for understanding consumer choice or estimating market demand. The paper explores the view of the human being, the "anthropology," that is implicit in the economic theory of the consumer and compares its "theological" implications with the corresponding theological anthropologies in the Judaeo-Christian tradition. The paper outlines the assumptions of consumer theory and then focuses on three aspects of the theory from a critical theological perspective: the individual in community, property ownership, and human destiny. The principal conclusion is that consumer theory, viewed from this perspective, leads to a reductionist and existentially harmful view of human beings. The maximization of individual satisfaction raises genuine ethical issues when viewed as a political and religious value. The paper argues that the issues could be ameliorated if economists would include more explicit treatment of a social dimension and ethical alternatives in consumer theory and if theologians would give greater attention to economic theory. (shrink)

The topic of developing professionalism dominated the content of many academic medicine publications and conference agendas during the past decade. Calls to address the development of professionalism among medical students and residents have come from professional societies, accrediting agencies, and a host of educators in the biomedical sciences. The language of the professionalism movement is now a given among those in academic medicine. We raise serious concerns about the professionalism discourse and how the specialized language of academic medicine disciplines has (...) defined, organized, contained, and made seemingly immutable a group of attitudes, values, and behaviors subsumed under the label of "professionalism." In particular, we argue that the professionalism discourse needs to pay more attention to the academic environment in which students are educated, that it should articulate specific positive behaviors, that the theory of professionalism must be constructed from a dialogue with those we are educating, and that this theoretical and practical discourse must aim at a deeper understanding of social justice and the role of medicine within a just society. (shrink)

In this chapter, the author analyzes Foucault's conception of subjectivity and his history of technologies of the self, the collections of practices by which subjectivity constitutes itself. The first section situates Foucault's conception of subjectivity in his overall body of work and intellectual context, particularly in relation to two figures in French philosophy. The second section explores the conception of the subject that Foucault develops in his late work. Having explained the importance of historical practices to his conception of subjectivity, (...) the third section considers his history of Western practices of the self, mapping the relative fortunes of what Foucault calls the “technologies” of ethics and spirituality. The fourth section explores Foucault's consideration of the contemporary implications of his position, his assessment of the scope for and importance of spiritual or ethical practices today. (shrink)

Immigrants lacking health insurance access the health care system through the emergency departments of non-profit hospitals. Because these persons lack health insurance, continued care can pose challenges to those institutions. I analyze the values of our health care institutions, utilizing a Walzerian approach that describes its appropriate sphere of justice. This particular sphere is dominated by a caring response to need. I suggest that the logic of this sphere would be best preserved by providing increased access to health insurance to (...) this population. This access would marry the rights of these members of our community to access care to our responsibility to contribute to financing of the system. I close with some considerations on what it means to be a member of the community. (shrink)

Contemporary bioethicists and scholars of ancient philosophy explore the import of classical ethics on pressing bioethical concerns.

ABSTRACTI consider objections to the use of living wills based upon the discontinuity of personal identity between the time of the execution of the directive anbd the time the person becomes incompetent. Recent authors, following Derek Parfit's “Complex View” of personal identity, have argued that there is often not sufficient identity interests between the competent person who executes the living will and the incompetent patient to warrant the use of the advance directive. I argue that such critics err by seeking (...) personal identity in a purely descriptive manner. By exploring Buchanan and Brock's concept of “surviving interests”, an argument is developed that certain future‐oriented acts have a normative force that contributes to the narrative unity which is constitutive of personal ideality. This narrative concept of the self is entailed by many of the our ordinary practices and challenges the philosophical consensus to view the self in a more dynamic and communitarian manner. (shrink)

I explore the possible meanings that the notion of the common morality can have in a contemporary communitarian approach to ethics and public policy. The common morality can be defined as the conditions for shared pursuit of the good or as the values, deliberations, traditions, and common construction of the narrative of a people. The former sense sees the common morality as the universal and invariant structures of morality while the second sense is much more contingent in nature. Nevertheless, the (...) communitarian sees both aspects as integral in devising solutions to public policy problems. I outline how both meanings follow from communitarian philosophical anthropology and illustrate how they work together when addressing a question such as that of providing universal health insurance in the United States. The common morality forms the basis of building an implicit consensus that is available to and reaffirmed by the shared reflections of the citizenry. (shrink)

In this essay, I take as a starting point Foucault’s rejection of two different ways of thinking about the future, prophecy and utopianism, and use this rejection as a basis for the elaboration of a more detailed rejection of them, invoking complexity-based epistemic limitations in relation to thinking about the future of political society. I follow Foucault in advocating immanent political struggle, which does not seek to build a determinate vision of the future but rather focuses on negating aspects of (...) the current conjuncture. I extend this argument into an ethical register, arguing that the same arguments apply mutatis mutandis to our personal lives. I conclude by engaging with Jacques Lacan’s account of subjectivity, and the interpretation of its political import furnished by Yannis Stavrakakis, drawing from these additional supports for my position, in particular the rejection of utopianism as an attempt to avoid limitation by the real. (shrink)

(2011). Mindfulness: diverse perspectives on its meaning, origins, and multiple applications at the intersection of science and dharma. Contemporary Buddhism: Vol. 12, Mindfulness: diverse perspectives on its meaning, origins, and multiple applications at the intersection of science and dharma, pp. 1-18. doi: 10.1080/14639947.2011.564811.